Studies on the etiology of the experimental neuropathy from industrial adhesive (glues)

Journal Cellular and Molecular Life Sciences (CMLS)
SpringerLink Date Monday, August 01, 2005

I. Franchini1, A. Cavatorta1, M. D'Errico1, M. De Santis1, G. Romita1, R. Gatti1, G. Juvarra1 and G. Palla1

(1) Istituto di Semeiotica Medica, Università degli Studi di Parma, Parma, Italy Summary

Chickens treated by paintbrushing with glue distillate (used in shoe industries), hydrocarbon mixture and TOCP in hexane, developed paralysis (4/5); in these, we have demonstrated a diffuse degeneration of the myelinic sheath of the peripheral and central neurites. Besides TOCP, cyclohexane (because of its higher concentration in the glue distillate and in the hydrocarbon mixture) may be indicated as responsible for occupational neuropathy.

Abstract is found here.

My notes: In our WG discussion group, many of the patients have complained of neuropathy in their extremities (feet and hands). Some symptoms of neuropathy is tingling and numbness. It is very interesting that glue used in the shoe industries could be a cause of this problem.